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EXT2 antibody (N-Term)

EXT2 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781795
  • Target See all EXT2 Antibodies
    EXT2 (Exostosin 2 (EXT2))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Pig
    Host
    • 26
    • 2
    • 1
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    This EXT2 antibody is un-conjugated
    Application
    • 23
    • 19
    • 14
    • 14
    • 13
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    NELLMAISDS DYYTDDINRA CLFVPSIDVL NQNTLRIKET AQAMAQLSRW
    Predicted Reactivity
    Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against EXT2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EXT2
    Top Product
    Discover our top product EXT2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 718 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EXT2 (Exostosin 2 (EXT2))
    Alternative Name
    EXT2 (EXT2 Products)
    Synonyms
    SOTV antibody, AI893565 antibody, EXT2 antibody, ext2 antibody, exostosin glycosyltransferase 2 antibody, exostoses (multiple) 2 antibody, exostoses (multiple) 3 antibody, exostosin glycosyltransferase 2 L homeolog antibody, EXT2 antibody, Ext2 antibody, EXT3 antibody, ext2.L antibody
    Background
    EXT2 is one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis.This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Alias Symbols: SOTV
    Protein Interaction Partner: UBC, GSKIP, SLC22A2, CDKN1A, ANXA7, TK1, SMN1, PFDN1, GALNT5, TRAP1, EXT2, EXT1, CLEC2L, CRB1, HYOU1, STK16, TCEB1, SNCG, RPS29, HNF4A, FABP4, CNTF,
    Protein Size: 718
    Molecular Weight
    82 kDa
    Gene ID
    2132
    NCBI Accession
    NM_000401, NP_000392
    UniProt
    Q93063
    Pathways
    Glycosaminoglycan Metabolic Process
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