Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

YWHAE antibody (Middle Region)

YWHAE Reactivity: Mouse, Zebrafish (Danio rerio), Guinea Pig, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792142
  • Target See all YWHAE Antibodies
    YWHAE (14-3-3 epsilon (YWHAE))
    Binding Specificity
    • 15
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 52
    • 37
    • 34
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse, Zebrafish (Danio rerio), Guinea Pig, Dog
    Host
    • 48
    • 4
    • 1
    Rabbit
    Clonality
    • 41
    • 12
    Polyclonal
    Conjugate
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This YWHAE antibody is un-conjugated
    Application
    • 41
    • 17
    • 13
    • 13
    • 13
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ELDTLSEESY KDSTLIMQLL RDNLTLWTSD MQGDGEEQNK EALQDVEDEN
    Predicted Reactivity
    Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against YWHAE. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human YWHAE
    Top Product
    Discover our top product YWHAE Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 255 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tak, Jang, Kim, Park, Suk, Yoon, Ahn, Lee, Joe: "14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization." in: Cellular signalling, Vol. 19, Issue 11, pp. 2379-87, (2007) (PubMed).

  • Target
    YWHAE (14-3-3 epsilon (YWHAE))
    Alternative Name
    YWHAE (YWHAE Products)
    Synonyms
    14-3-3 antibody, 14-3-3 epsilon antibody, 14-3-3-e antibody, 14-3-3-epsilon antibody, 14-3-30epsilon antibody, 14-3-3EPSILON antibody, 14-3-3e antibody, 14-3-3omicron antibody, 1433epsilon antibody, 143E_DROME antibody, CG31196 antibody, CT24092 antibody, D14-3-3e antibody, D14-3-3epsilon antibody, Dmel\\CG31196 antibody, EK3-5 antibody, PAR-5 antibody, PAR5 antibody, Par-5 antibody, SR3-9 antibody, Su(Raf)3B antibody, anon-WO0172774.141 antibody, anon-WO02059370.52 antibody, d14-3-3epsilon antibody, eps antibody, l(3)j2B10 antibody, par-5 antibody, 14-3-3epsilon antibody, kcip-1 antibody, mdcr antibody, mds antibody, LOC581376 antibody, Ywhae antibody, ACYPI002517 antibody, YWHAE antibody, 14-3-3E antibody, KCIP-1 antibody, MDCR antibody, MDS antibody, AU019196 antibody, fe38c12 antibody, wu:fb48f06 antibody, wu:fe38c12 antibody, wu:fi22e10 antibody, ywhae antibody, zgc:55377 antibody, zgc:77062 antibody, CG31196 gene product from transcript CG31196-RD antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon antibody, 14-3-3 epsilon antibody, 14-3-3 epsilon protein antibody, 14-3-3 protein epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 antibody, 14-3-3epsilon antibody, ywhae antibody, LOC581376 antibody, Ywhae antibody, HCAG_04173 antibody, PTRG_02836 antibody, PTRG_04459 antibody, UREG_07864 antibody, YWHAE antibody, ywhae.S antibody, ywhae1 antibody
    Background
    YWHAE is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAE binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. The binding generally results in the modulation of the activity of the binding partner.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: 14-3-3E, FLJ45465, KCIP-1, MDCR, MDS
    Protein Interaction Partner: DTL, HUWE1, FAM53C, FBXW11, SORBS2, UBC, ABL1, GRB10, SIK2, CEP57, SIK3, TP53, IRS4, CBL, TUBB2A, TWF2, PROSC, FERMT2, PDIA4, RAP1GDS1, PTMA, PPP1R2, PDHB, PAK2, PAFAH1B2, YWHAH, XPO1, VCL, GSS, G6PD, EIF5, TBCB, CAPNS1, CAPN2, ALDH7A1, ATIC, ASNS, SCPEP1
    Protein Size: 255
    Molecular Weight
    29 kDa
    Gene ID
    7531
    NCBI Accession
    NM_006761, NP_006752
    UniProt
    P62258
    Pathways
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
You are here:
Support