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Src antibody (N-Term)

Name: Src antibody (N-Term)
SKU: ABIN2779669
Price: 472.77 USD
Availability: InStock

Src Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated

WB Suggested Anti-SRC Antibody Titration: 0.

Western Blotting (WB) image for anti-Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) antibody (ABIN2779669)

Host: Mouse Target Name: SRC Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml

Host: Mouse Target Name: SRC Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml

4 images

Catalog No. ABIN2779669

Datasheet as PDF

Target See all Src Antibodies

Src (Proto-oncogene tyrosine-protein kinase Src (Src))
Binding Specificity
28

25

21

19

19

18

15

14

11

8

8

7

6

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivity
225

142

119

9

7

6

5

5

4

4

2

1

1

1

1
Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig
Host
238

19

1
Rabbit
Compatible Secondaries
Clonality
216

42
Polyclonal
Conjugate
123

21

18

16

12

11

6

6

6

6

6

6

4

4

4

4

4

1
This Src antibody is un-conjugated
Application
192

134

63

55

53

35

30

30

23

12

9

7

4

3

1
Western Blotting (WB)

Sequence

QTPSKPASAD GHRGPSAAFA PAAAEPKLFG GFNSSDTVTS PQRAGPLAGG

Predicted Reactivity

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics

This is a rabbit polyclonal antibody against SRC. It was validated on Western Blot.

Purification

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SRC

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anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52), (N-Term) antibody
Src Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB41141 unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 1F11 unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr530) antibody
Src Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-80) antibody
Src Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
KO Validated Src Reactivity: Human WB, IF, IP Host: Rabbit Monoclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibody
Src Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52) antibody
Src Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Rabbit Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr419) antibody
Src Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (Tyr1172) antibody
Src Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilutions should be determined experimentally by the investigator.

Comment

Antigen size: 536 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Alternative Name

SRC (Src Products)

Synonyms

AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody

Target Type

Viral Protein

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer.
Alias Symbols: ASV, SRC1, c-SRC, p60-Src
Protein Interaction Partner: PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, NEDD4, MAPT, ESR1, CA3, ARRB2, UBC, SRC, SPRR2A, IKBKG, CBLC, ZNF658B, TLR4, RGS16, PTGER4, EGFR, ARRB1, TNFRSF1A, KHDRBS1, SYK, CD44, ENO1, ANXA7, PIK3
Protein Size: 536

Molecular Weight

60 kDa

Gene ID

6714

NCBI Accession

NM_005417, NP_005408

UniProt

P12931

Pathways

JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling