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PNP antibody (AA 161-189)

NP Reactivity: Human, Mouse, Rat WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5647213
  • Target See all PNP (NP) Antibodies
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Binding Specificity
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 161-189
    Reactivity
    • 37
    • 11
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 38
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 41
    • 4
    Polyclonal
    Conjugate
    • 26
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNP antibody is un-conjugated
    Application
    • 25
    • 18
    • 12
    • 9
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity purified
    Immunogen
    Amino acids 161-189 (AMSDAYDRTMRQRALSTWKQMGEQRELQE-human) were used as the immunogen for the Purine nucleoside phosphorylase antibody.
    Isotype
    IgG
  • Application Notes
    Optimal dilution of the Purine nucleoside phosphorylase antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Flow cytometry: 1-3 μg/10^6 cells
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Alternative Name
    PNP / Purine Nucleoside Phosphorylase (NP Products)
    Synonyms
    NP antibody, PRO1837 antibody, PUNP antibody, Np antibody, AL024301 antibody, AU015798 antibody, Np-1 antibody, Np-2 antibody, Pnp1 antibody, purine nucleoside phosphorylase antibody, purine-nucleoside phosphorylase antibody, PNP antibody, Pnp antibody
    Target Type
    Viral Protein
    Background
    The PNP gene encodes Purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
    UniProt
    P00491
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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