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NPM1 antibody (AA 1-294)

NPM1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3B2 unconjugated
Catalog No. ABIN562035
  • Target See all NPM1 Antibodies
    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
    Binding Specificity
    • 21
    • 15
    • 15
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-294
    Reactivity
    • 147
    • 105
    • 76
    • 13
    • 12
    • 10
    • 9
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 142
    • 28
    • 1
    • 1
    Mouse
    Clonality
    • 139
    • 34
    Monoclonal
    Conjugate
    • 99
    • 15
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This NPM1 antibody is un-conjugated
    Application
    • 121
    • 61
    • 48
    • 35
    • 31
    • 28
    • 27
    • 15
    • 14
    • 13
    • 7
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant NPM1.
    Sequence
    MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAA DEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAK MQASIEKGGS LPKVEAKFIN YVKNCFRMTD QEAIQDLWQW RKSL
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    NPM1 (AAH02398.1, 1 a.a. ~ 294 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    3B2
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • El Hajj, Dassouki, Berthier, Raffoux, Ades, Legrand, Hleihel, Sahin, Tawil, Salameh, Zibara, Darwiche, Mohty, Dombret, Fenaux, de Thé, Bazarbachi: "Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells." in: Blood, Vol. 125, Issue 22, pp. 3447-54, (2015) (PubMed).

  • Target
    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
    Alternative Name
    NPM1 (NPM1 Products)
    Synonyms
    B23 antibody, NPM antibody, NO38 antibody, Npm antibody, B23NP antibody, npm4 antibody, npm antibody, CG7917 antibody, CRP1 antibody, Crp1 antibody, Dmel\\CG7917 antibody, dNLP antibody, dNLP-S antibody, p22 antibody, npm1 antibody, sb:cb487 antibody, nucleophosmin 1 antibody, nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog antibody, nucleophosmin 1b antibody, Nucleophosmin antibody, nucleophosmin antibody, nucleophosmin (nucleolar phosphoprotein B23, numatrin) antibody, Nucleoplasmin antibody, nucleophosmin 1a antibody, NPM1 antibody, Npm1 antibody, npm1.L antibody, npm1b antibody, npm antibody, Nlp antibody, npm1a antibody
    Background
    Full Gene Name: nucleophosmin (nucleolar phosphoprotein B23, numatrin)
    Synonyms: B23,MGC104254,NPM
    Gene ID
    4869
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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