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SLUG antibody (Middle Region)

SNAI2 Reactivity: Human, Mouse, Rat, Cow, Sheep, Rabbit, Dog, Horse, Guinea Pig, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777851
  • Target See all SLUG (SNAI2) Antibodies
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Binding Specificity
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 50
    • 18
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Sheep, Rabbit, Dog, Horse, Guinea Pig, Saccharomyces cerevisiae
    Host
    • 39
    • 11
    Rabbit
    Clonality
    • 40
    • 9
    Polyclonal
    Conjugate
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SLUG antibody is un-conjugated
    Application
    • 27
    • 20
    • 11
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SDTSSKDHSG SESPISDEEE RLQSKLSDPH AIEAEKFQCN LCNKTYSTFS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%
    Characteristics
    This is a rabbit polyclonal antibody against SNAI2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SNAI2
    Top Product
    Discover our top product SNAI2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 268 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Alternative Name
    SNAI2 (SNAI2 Products)
    Synonyms
    Slug antibody, Slugh antibody, Snail2 antibody, snail family transcriptional repressor 2 antibody, snail family zinc finger 2 antibody, Snai2 antibody
    Background
    SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC10182, SLUG, SLUGH1, WS2D, SNAIL2
    Protein Interaction Partner: SAT1, TRIM23, PPP2R2D, PPP6R3, STUB1, TJP2, UBC, TP53, PSMD3, PSMD1, PSMC1, PSMA3, PPP2CB, GSK3B, MDM2, APP, KDM1A, HDAC1, CHD4, Sin3a, HDAC2,
    Protein Size: 268
    Molecular Weight
    30 kDa
    Gene ID
    6591
    NCBI Accession
    NM_003068, NP_003059
    UniProt
    O43623
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