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CD51 antibody (C-Term)

ITGAV Reactivity: Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789883
  • Target See all CD51 (ITGAV) Antibodies
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Binding Specificity
    • 16
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 93
    • 49
    • 23
    • 8
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep
    Host
    • 66
    • 28
    • 6
    Rabbit
    Clonality
    • 56
    • 43
    Polyclonal
    Conjugate
    • 52
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD51 antibody is un-conjugated
    Application
    • 49
    • 44
    • 28
    • 25
    • 19
    • 14
    • 14
    • 12
    • 11
    • 9
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PVWVIILAVL AGLLLLAVLV FVMYRMGFFK RVRPPQEEQE REQLQPHENG
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ITGAV. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV
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  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1002 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Alternative Name
    ITGAV (ITGAV Products)
    Synonyms
    1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
    Background
    ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
    Alias Symbols: CD51, DKFZp686A08142, MSK8, VNRA
    Protein Interaction Partner: UBC, EPHA2, THBS1, FN1, KRT3, MCAT, FBXO6, BCAR1, PXN, PHKA2, CSF1R, CBL, MMP2, ILK, PLP1, CALR, ANGPTL3, EDIL3, CYR61, PAK4, ITGB8, ADAM9, AUP1, CD47, PTK2, MMP14, P2RY2, L1CAM, AZGP1, TGFB1, THY1, F2R, PDGFRA, ITGB3, SPP1, ITGB5, ITGB6, ITGB1, NID1, ICA
    Protein Size: 1002
    Molecular Weight
    100 kDa
    Gene ID
    3685
    NCBI Accession
    NM_001144999, NP_001138471
    UniProt
    E7EWZ6
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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