NUP98 antibody (GLFG Motif, N-Term)
(2 references)-
- Target See all NUP98 Antibodies
- NUP98 (Nucleoporin 98kDa (NUP98))
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Binding Specificity
- GLFG Motif, N-Term
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Reactivity
- Human, Mouse, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NUP98 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Cross-Reactivity (Details)
- Not tested in other species.
- Purification
- Purified
- Sterility
- Sterile filtered
- Immunogen
- Synthetic peptides containing conserved N-terminal sequence, GLFG, of Nup98 protein of Tetrahymena thermophila.
- Clone
- 21A10
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product NUP98 Primary Antibody
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anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibody
NUP98 Reactivity: Human, Mouse, Rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB Host: Rat Monoclonal 2H10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (FGxxN Motif), (N-Term) antibodyNUP98 Reactivity: Human, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF Host: Mouse Monoclonal 13C2 unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 965-1110) antibodyNUP98 Reactivity: Human WB, ELISA, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 Reactivity: Human WB, ELISA, IF, IHC Host: Rabbit Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Nucleoporin 98kDa (NUP98) (AA 621-920) antibodyNUP98 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 Reactivity: Human WB, IP Host: Mouse Monoclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-606) antibodyNUP98 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibodyNUP98 Reactivity: Human WB, ELISA, IF, ICC, DB Host: Rat Monoclonal 2H10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 36-85) antibodyNUP98 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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1) Western blotting: S. cerevisiae, S. pombe. Not suitable for human. Clone 13C2 is recommended for WB in human Tetrahymena and yeasts.
2) Most suitable for Immunofluorescence staining / Immunocytochemistry for human, mouse, Tetrahymena, S. cerevisiae, S. pombe. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol. Azide- and carrier protein-free.
- Preservative
- Azide free
- Storage
- -20 °C
- Storage Comment
- Upon arrival centrifuge briefly and store at -20 C.
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: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
: "Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 7, pp. 661-9, (2010) (PubMed).
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: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
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- Target
- NUP98 (Nucleoporin 98kDa (NUP98))
- Alternative Name
- Nup98 (NUP98 Products)
- Synonyms
- CG10198 antibody, CG10201 antibody, Dmel\\CG10198 antibody, Nup 96 antibody, Nup 98 antibody, Nup-98 antibody, Nup96 antibody, Nup98 antibody, Nup98-Nup96 antibody, Nup98/96 antibody, l(3)95BCd antibody, nup145 antibody, nup98-96 antibody, GB12688 antibody, NUP98 antibody, 4732457F17 antibody, AI849286 antibody, im:7151238 antibody, zgc:113968 antibody, zgc:63593 antibody, ADIR2 antibody, NUP196 antibody, NUP96 antibody, Nucleoporin 98-96kD antibody, nuclear pore complex protein Nup98-Nup96 antibody, nucleoporin 98 antibody, nucleoporin 98kDa antibody, nucleoporin 98 L homeolog antibody, Nup98-96 antibody, LOC408335 antibody, NUP98 antibody, LOC587580 antibody, Nup98 antibody, nup98 antibody, nup98.L antibody
- Background
- Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope and highly conserved in eukaryotes. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine- glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 also plays a specific role in the RNA export. In addition, Nup98 plays roles in several important biological events such as gene expression, mitotic checkpoint, and pathogenesis Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. In ciliates, a unicellular organism having two functionally distinct nuclei, GLFG-Nup98 is present in one of the nuclei and a distinct Nup98 ortholog is present in the other nucleus, and these different Nup98s participate in a nucleus-selective transport mechanism.
- UniProt
- P52948
- Pathways
- Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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