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OAZ1 antibody (AA 1-68)

OAZ1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7162292
  • Target See all OAZ1 Antibodies
    OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-68
    Reactivity
    • 18
    • 14
    • 6
    Human
    Host
    • 17
    • 1
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAZ1 antibody is un-conjugated
    Application
    • 8
    • 7
    • 5
    • 1
    Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Ornithine decarboxylase antizyme 1 protein (1-68AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
    Alternative Name
    OAZ1 (OAZ1 Products)
    Synonyms
    AZI antibody, OAZ antibody, AZ-1 antibody, AZ1 antibody, Antizyme antibody, ODC-Az antibody, Oaz antibody, ODCAC antibody, oaz antibody, AZS antibody, oaz1 antibody, ornithine decarboxylase antizyme 1 antibody, ornithine decarboxylase antizyme 1 S homeolog antibody, ornithine decarboxylase antizyme 1a antibody, OAZ1 antibody, Oaz1 antibody, oaz1.S antibody, oaz1a antibody
    Background

    Background: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake by binding to and targeting ODC1 for degradation (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.

    Aliases: Antizyme 1 antibody, Antizyme antibody, AZI antibody, MGC138338 antibody, OAZ 1 antibody, OAZ antibody, OAZ1 antibody, OAZ1_HUMAN antibody, ODC Az antibody, ODC-Az antibody, Ornithine decarboxylase antizyme 1 antibody, Ornithine decarboxylase antizyme antibody

    UniProt
    P54368
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