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OPA1 antibody (AA 661-960)

OPA1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6145031
  • Target See all OPA1 Antibodies
    OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
    Binding Specificity
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 661-960
    Reactivity
    • 45
    • 29
    • 29
    • 17
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 41
    • 4
    Rabbit
    Clonality
    • 34
    • 11
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This OPA1 antibody is un-conjugated
    Application
    • 29
    • 14
    • 14
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    TDKQLPNKAV EVAWETLQEE FSRFMTEPKG KEHDDIFDKL KEAVKEESIK RHKWNDFAED SLRVIQHNAL EDRSISDKQQ WDAAIYFMEE ALQARLKDTE NAIENMVGPD WKKRWLYWKN RTQEQCVHNE TKNELEKMLK CNEEHPAYLA SDEITTVRKN LESRGVEVDP SLIKDTWHQV YRRHFLKTAL NHCNLCRRGF YYYQRHFVDS ELECNDVVLF WRIQRMLAIT ANTLRQQLTN TEVRRLEKNV KEVLEDFAED GEKKIKLLTG KRVQLAEDLK KVREIQEKLD AFIEALHQEK
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 661-960 of human OPA1 (NP_056375.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." in: Biological trace element research, (2018) (PubMed).

  • Target
    OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
    Alternative Name
    OPA1 (OPA1 Products)
    Synonyms
    1200011N24Rik antibody, AI225888 antibody, AI847218 antibody, lilr3 antibody, mKIAA0567 antibody, MGM1 antibody, NPG antibody, NTG antibody, largeG antibody, fk62d06 antibody, wu:fb77a10 antibody, wu:fk62d06 antibody, zgc:92092 antibody, OPA1, mitochondrial dynamin like GTPase antibody, optic atrophy 1 (autosomal dominant) antibody, Opa1 antibody, OPA1 antibody, opa1 antibody
    Background
    This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.,OPA1,BERHS,MGM1,MTDPS14,NPG,NTG,largeG,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,Cardiac metabolism,OPA1
    Molecular Weight
    111 kDa/115 kDa
    Gene ID
    4976
    UniProt
    O60313
    Pathways
    Tube Formation
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