FAM126A antibody (AA 1-100)
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- Target See all FAM126A Antibodies
- FAM126A (Family with Sequence Similarity 126, Member A (FAM126A))
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Binding Specificity
- AA 1-100
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAM126A antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Hyccin
- Isotype
- IgG
- Top Product
- Discover our top product FAM126A Primary Antibody
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anti-Family with Sequence Similarity 126, Member A (FAM126A) antibody
FAM126A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Family with Sequence Similarity 126, Member A (FAM126A) (AA 342-391) antibodyFAM126A Reactivity: Human, Mouse, Cow, Dog, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Family with Sequence Similarity 126, Member A (FAM126A) (C-Term) antibodyFAM126A Reactivity: Human, Mouse, Cow, Dog, Rat, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- FAM126A (Family with Sequence Similarity 126, Member A (FAM126A))
- Alternative Name
- FAM126A/Hyccin (FAM126A Products)
- Synonyms
- DRCTNNB1A antibody, HCC antibody, HLD5 antibody, HYCC1 antibody, AB030242 antibody, Drctnnb1a antibody, RGD1562906 antibody, zgc:77228 antibody, fam126a antibody, family with sequence similarity 126 member A antibody, family with sequence similarity 126, member A antibody, family with sequence similarity 126 member A S homeolog antibody, FAM126A antibody, Fam126a antibody, fam126a antibody, fam126a.S antibody
- Background
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Synonyms: Down regulated by Ctnnb1 a, Down regulated by CTNNB1 protein A, Down-regulated by CTNNB1 protein A, DRCTNNB1A, FAM126A, Family with sequence similarity 126 member A, HCC, HLD5, HYCC1, HYCCI_HUMAN antibody Hyccin, Protein FAM126A.
Background: Hyccin is a 521 amino acid cytoplasmic protein that is widely expressed with highest levels found in heart, brain, placenta, spleen and testis. Belonging to the FAM126 family, hyccin may play a role in the -catenin/Lef signaling pathway. Hyccin is likely involved in the process of myelination of the central and peripheral nervous system. Defects in the gene encoding hyccin are the cause of leukodystrophy hypomyelinating type 5 (HLD5), which is characterized by congenital cataract, progressive neurologic impairment and diffuse myelin deficiency. Individuals affected by HLD5 experience progressive pyramidal and cerebellar dysfunction along with muscle weakness in the lower limbs. Hyccin exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 7.
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