ARHGEF3 antibody (AA 211-240)
(1 reference)-
- Target See all ARHGEF3 Antibodies
- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
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Binding Specificity
- AA 211-240
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARHGEF3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This ARHGEF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ARHGEF3.
- Clone
- RB27451
- Isotype
- Ig Fraction
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibody
ARHGEF3 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 33-142) antibodyARHGEF3 Reactivity: Human ELISA Host: Mouse Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) antibodyARHGEF3 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 Reactivity: Human, Monkey WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibodyARHGEF3 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 1-324) antibodyARHGEF3 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).
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: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).
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- Target
- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
- Alternative Name
- ARHGEF3 (ARHGEF3 Products)
- Synonyms
- MGC82822 antibody, ARHGEF3 antibody, si:ch211-258l4.8 antibody, MGC108040 antibody, DKFZp459N027 antibody, GEF3 antibody, STA3 antibody, XPLN antibody, 1200004I24Rik antibody, 9830169H03Rik antibody, C76747 antibody, Xpln antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antibody, Rho guanine nucleotide exchange factor 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antibody, arhgef3.1.S antibody, ARHGEF3 antibody, arhgef3 antibody, arhgef3.1 antibody, Arhgef3 antibody
- Background
- Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 59783
- Gene ID
- 50650
- NCBI Accession
- NP_001122087, NP_001122088, NP_062455
- UniProt
- Q9NR81
- Pathways
- Neurotrophin Signaling Pathway
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