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PAM antibody (AA 338-497)

PAM Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7162786
  • Target See all PAM Antibodies
    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 338-497
    Reactivity
    • 22
    • 11
    • 11
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 18
    • 3
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAM antibody is un-conjugated
    Application
    • 11
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Peptidyl-glycine alpha-amidating monooxygenase protein (338-497AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
    Alternative Name
    PAM (PAM Products)
    Synonyms
    PAL antibody, PHM antibody, pal antibody, phm antibody, pamb antibody, CG3832 antibody, Dmel\\CG3832 antibody, dPHM antibody, AE-I antibody, PAL-A antibody, PHM-A antibody, pama antibody, si:dkeyp-35f12.2 antibody, peptidylglycine alpha-amidating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase S homeolog antibody, Peptidylglycine-alpha-hydroxylating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase L homeolog antibody, PAM antibody, Pam antibody, pam.S antibody, CHLREDRAFT_150435 antibody, sce7070 antibody, pam antibody, Phm antibody, pam.L antibody
    Background

    Background: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.

    Aliases: AMD_HUMAN antibody, PAL antibody, PAM antibody, Pancreatic peptidylglycine alpha amidating monooxygenase antibody, Peptidyl alpha amidating enzyme antibody, Peptidyl alpha hydroxyglycine alpha amidating lyase antibody, Peptidyl-alpha-hydroxyglycine alpha-amidating lyase antibody, Peptidylamidoglycolate lyase antibody, Peptidylglycine 2 hydroxylase antibody, Peptidylglycine alpha amidating monooxygenase antibody, Peptidylglycine alpha hydroxylating monooxygenase antibody, PHM antibody

    UniProt
    P19021