Importin 11 antibody (N-Term)
-
- Target See all Importin 11 (IPO11) Antibodies
- Importin 11 (IPO11)
-
Binding Specificity
- AA 56-85, N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Importin 11 antibody is un-conjugated
-
Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human IPO11.
- Clone
- RB23487
- Isotype
- Ig Fraction
-
anti-Importin 11 (IPO11) antibody
IPO11 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Importin 11 (IPO11) antibodyIPO11 Reactivity: Human WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 891-920), (C-Term) antibodyIPO11 Reactivity: Human WB Host: Rabbit Polyclonal RB24373 unconjugated
anti-Importin 11 (IPO11) (AA 1-50) antibodyIPO11 Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 328-377) antibodyIPO11 Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 776-975) antibodyIPO11 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 1-50) antibodyIPO11 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
-
- Target
- Importin 11 (IPO11)
- Alternative Name
- IPO11 (IPO11 Products)
- Synonyms
- MGC83107 antibody, IPO11 antibody, slrn antibody, ranbp11 antibody, RanBP11 antibody, 1700081H05Rik antibody, 2510001A17Rik antibody, AI314624 antibody, AW555235 antibody, E330021B14Rik antibody, Ranbp11 antibody, importin 11 S homeolog antibody, importin 11 antibody, importin-11 antibody, ipo11.S antibody, ipo11 antibody, IPO11 antibody, AFUA_1G03590 antibody, BDBG_04626 antibody, LOC100162908 antibody, Ipo11 antibody
- Background
- IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
- Molecular Weight
- 112535
- Gene ID
- 51194
- NCBI Accession
- NP_001128251, NP_057422
- UniProt
- Q9UI26
- Pathways
- Protein targeting to Nucleus
-
