CHMP5 antibody
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- Target See all CHMP5 Antibodies
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHMP5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- Cross-Reactivity
- Human, Mouse
- Characteristics
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Rabbit Polyclonal antibody to CHMP5 (chromatin modifying protein 5)
CHMP5 antibody [N1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CHMP5. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Charged Multivesicular Body Protein 5 (CHMP5) (AA 1-219) antibody
CHMP5 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 5 (CHMP5) (AA 178-204), (C-Term) antibodyCHMP5 Reactivity: Human WB Host: Rabbit Polyclonal RB38584 unconjugated
anti-Charged Multivesicular Body Protein 5 (CHMP5) (C-Term) antibodyVerified CHMP5 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2
Validation: Comparison, Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.7 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- Alternative Name
- charged multivesicular body protein 5 (CHMP5 Products)
- Synonyms
- SNF7DC2 antibody, cgi-34 antibody, hspc177 antibody, pnas-2 antibody, vps60 antibody, chmp5 antibody, zgc:64125 antibody, C9orf83 antibody, HSPC177 antibody, PNAS-2 antibody, Vps60 antibody, 2210412K09Rik antibody, AW545668 antibody, RGD1305968 antibody, charged multivesicular body protein 5 S homeolog antibody, charged multivesicular body protein 5b antibody, charged multivesicular body protein 5 antibody, charged multivesicular body protein 5 L homeolog antibody, chromatin modifying protein 5 antibody, chmp5.S antibody, chmp5b antibody, CHMP5 antibody, chmp5.L antibody, chmp5 antibody, Chmp5 antibody
- Background
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CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]
Cellular Localization: Cytoplasm , cytosol , Endosome membrane, Peripheral membrane protein , Cytoplasm , cytosol , Endosome membrane - Molecular Weight
- 25 kDa
- Gene ID
- 51510
- UniProt
- Q9NZZ3
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