APRT antibody (N-Term)
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- Target See all APRT Antibodies
- APRT (Adenine Phosphoribosyltransferase (APRT))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rat, Dog, Cow, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APRT antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK
- Predicted Reactivity
- Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%
- Characteristics
- This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human APRT
- Top Product
- Discover our top product APRT Primary Antibody
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anti-Adenine Phosphoribosyltransferase (APRT) (AA 12-40), (N-Term) antibody
APRT Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB20509 unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 143-170), (C-Term) antibodyAPRT Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal RB20510 unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 1-180) antibodyAPRT Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 1-180) antibodyAPRT Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (Internal Region) antibodyAPRT Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 149-179) antibodyAPRT Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 1-180) antibodyAPRT Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) antibodyAPRT Reactivity: Human WB, IHC, FACS, IF/ICC Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 1-180) antibodyAPRT Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Adenine Phosphoribosyltransferase (APRT) (AA 1-180) antibodyAPRT Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 180 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- APRT (Adenine Phosphoribosyltransferase (APRT))
- Alternative Name
- APRT (APRT Products)
- Synonyms
- Tb07.43M14.200 antibody, Tb07.43M14.180 antibody, C85684 antibody, AMP antibody, APRTD antibody, adenine phosphoribosyltransferase antibody, adenine phosphoribosyl transferase antibody, CND05020 antibody, Tb927.7.1790 antibody, Tb927.7.1780 antibody, Arnit_0941 antibody, Saut_1231 antibody, Fbal_1180 antibody, PH_RS07970 antibody, PF_RS08760 antibody, PAB_RS02560 antibody, Aprt antibody, APRT antibody
- Background
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Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
Protein Interaction Partner: UBC, FN1, VCAM1, MLH1, ITGA4, NAPRT, HECW2, GMPS, UMPS, HPRT1, APP, IKBKG, APRT, VHL,
Protein Size: 180 - Molecular Weight
- 20 kDa
- Gene ID
- 353
- NCBI Accession
- NM_000485, NP_000476
- UniProt
- P07741
- Pathways
- Ribonucleoside Biosynthetic Process
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