Prohibitin antibody
(2 references)-
- Target See all Prohibitin (PHB) Antibodies
- Prohibitin (PHB)
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Prohibitin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human PHB expressed in E. coli.
- Clone
- 5H7
- Isotype
- IgG1
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anti-Prohibitin (PHB) antibody
KO Validated PHB Reactivity: Human WB, IF, IHC (p), IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 1-272) antibodyPHB Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3F4-2B2 unconjugated
anti-Prohibitin (PHB) (AA 177-272) antibodyPHB Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB Reactivity: Human WB, IHC, IF, StM Host: Mouse Monoclonal PHB-3194 unconjugated
anti-Prohibitin (PHB) (AA 73-272) antibodyPHB Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 89-117) antibodyPHB Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB17513 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB Reactivity: Human WB, IHC, IF, StM Host: Mouse Monoclonal PHB-3231 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal PHB-3230 unconjugated
anti-Prohibitin (PHB) (AA 92-121), (N-Term) antibodyPHB Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB10625 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal PHB-3193 unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." in: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).
: "Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling." in: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 1023-8, (2009) (PubMed).
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: "Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." in: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).
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- Target
- Prohibitin (PHB)
- Alternative Name
- PHB (PHB Products)
- Synonyms
- phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody
- Background
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Description: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Aliases: PHB1
- Molecular Weight
- 30 kDa
- Gene ID
- 5245
- HGNC
- 5245
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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