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NHP2 antibody

NHP2 Reactivity: Human, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7246787
  • Target See all NHP2 Antibodies
    NHP2 (NHP2 Ribonucleoprotein (NHP2))
    Reactivity
    • 10
    • 2
    • 2
    Human, Mouse
    Host
    • 10
    Rabbit
    Clonality
    • 10
    Polyclonal
    Conjugate
    • 6
    • 2
    • 1
    • 1
    This NHP2 antibody is un-conjugated
    Application
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human NHP2
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.96 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NHP2 (NHP2 Ribonucleoprotein (NHP2))
    Alternative Name
    NHP2 (NHP2 Products)
    Synonyms
    DKCB2 antibody, NHP2P antibody, NOLA2 antibody, 2410130M07Rik antibody, D11Ertd175e antibody, Nola2 antibody, NHP2 ribonucleoprotein antibody, NHP2 antibody, Nhp2 antibody
    Background
    This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 17 kDa

    UniProt
    Q9NX24
    Pathways
    Telomere Maintenance
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