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SUZ12 antibody (C-Term)

SUZ12 Reactivity: Human, Mouse WB, IF, ChIP, ChIP-seq Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6972836
  • Target See all SUZ12 Antibodies
    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
    Binding Specificity
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 41
    • 23
    • 12
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 36
    • 7
    Rabbit
    Clonality
    • 26
    • 17
    Polyclonal
    Conjugate
    • 32
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SUZ12 antibody is un-conjugated
    Application
    • 30
    • 18
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
    Characteristics
    Suz12 (Suppressor-of-Zeste 12 protein, also designated as ChET9, JJAZ1 protein) is a component of the Polycomb group complexes 2, 3 and 4 (PRC2, PRC3 and PRC4), which also contain the histone methyltransferase EZH2, EED (Embryonic Ectoderm Development protein) protein and the histone-binding proteins RbAP46 and RbAP48. PRC2 is responsible for di- and trimethylation of histone 3 at lysine 27 (Histone H3K27me2 and Histone H3K27me3), which leads to transcriptional repression of the target genes. Suz12 is a nuclear protein belonging to the VEFS family. Suz12 contains a zinc-finger binding motif and a VEFS box, which is required for the interaction between Suz12 and EZH2. Suz12 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    Purification
    Affinity Purified
    Immunogen
    This Suz12 antibody was raised against a peptide corresponding to the C-terminus of human Suz12.
    Isotype
    IgG
    Top Product
    Discover our top product SUZ12 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 30 % glycerol, 0.035 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
    Alternative Name
    Suz12 (SUZ12 Products)
    Synonyms
    fc31h10 antibody, im:7153578 antibody, si:dkey-10p5.2 antibody, suz12 antibody, wu:fc31h10 antibody, 2610028O16Rik antibody, AI195385 antibody, AU016842 antibody, AW536442 antibody, D11Ertd530e antibody, mKIAA0160 antibody, Xsuz12 antibody, chet9 antibody, jjaz1 antibody, CHET9 antibody, ChET 9 protein antibody, JJAZ1 antibody, suz12l antibody, zgc:100863 antibody, SUZ12 polycomb repressive complex 2b subunit antibody, SUZ12 polycomb repressive complex 2 subunit antibody, suppressor of zeste 12 homolog (Drosophila) antibody, SUZ12 polycomb repressive complex 2 subunit S homeolog antibody, SUZ12 polycomb repressive complex 2a subunit antibody, suz12b antibody, Suz12 antibody, SUZ12 antibody, suz12.S antibody, suz12a antibody
    Molecular Weight
    95 kDa
    NCBI Accession
    NP_056170
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