ATP6V0C antibody (Middle Region)
-
- Target See all ATP6V0C Antibodies
- ATP6V0C (ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C))
-
Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ATP6V0C antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- VVAVLIANSL NDDISLYKSF LQLGAGLSVG LSGLAAGFAI GIVGDAGVRG
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 90%, Sheep: 86%
- Characteristics
- This is a rabbit polyclonal antibody against ATP6V0C. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ATP6V0C
-
anti-ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C) (AA 1-100) antibody
ATP6V0C Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C) (AA 100-126), (C-Term) antibodyATP6V0C Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB24576 unconjugated
anti-ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C) antibodyATP6V0C Reactivity: Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C) (AA 100-126) antibodyATP6V0C Reactivity: Human, Mouse WB, IHC (p), IHC Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 155 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- ATP6V0C (ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C (ATP6V0C))
- Alternative Name
- ATP6V0C (ATP6V0C Products)
- Synonyms
- ATP6C antibody, ATP6L antibody, ATPL antibody, VATL antibody, VPPC antibody, Vma3 antibody, Atp6c antibody, Atp6c2 antibody, Atp6l antibody, Atpl antibody, Atpl-rs1 antibody, PL16 antibody, CHUNP6904 antibody, atp6l antibody, atp6v0c antibody, cb993 antibody, fb57d09 antibody, wu:fb57d09 antibody, atp6c antibody, atpl antibody, ductin antibody, vatl antibody, vma3 antibody, PLP antibody, wu:fc74d11 antibody, zgc:111904 antibody, zgc:77708 antibody, ATPase H+ transporting V0 subunit c antibody, ATPase, H+ transporting, lysosomal V0 subunit C antibody, ATPase H+ transporting V0 subunit C antibody, ATPase, H+ transporting, lysosomal, V0 subunit ca antibody, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c antibody, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog antibody, V-type proton ATPase 16 kDa proteolipid subunit antibody, ATPase, H+ transporting, lysosomal, V0 subunit cb antibody, ATP6V0C antibody, Atp6v0c antibody, atp6v0ca antibody, atp6v0c antibody, atp6v0c.L antibody, LOC696755 antibody, atp6v0cb antibody
- Background
-
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.
Alias Symbols: ATP6C, ATP6L, ATPL, VATL, Vma3, VPPC
Protein Interaction Partner: SMIM3, UBC, PSMA3, MSR1, EDA, CERS2, CLIC1, RNF182, MARK3, ARF6,
Protein Size: 155 - Molecular Weight
- 16 kDa
- Gene ID
- 527
- NCBI Accession
- NM_001694, NP_001685
- UniProt
- P27449
- Pathways
- Transition Metal Ion Homeostasis, Proton Transport
-
