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UBE2K antibody (AA 109-139)

UBE2K Reactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB4144 unconjugated
Catalog No. ABIN1882088
  • Target See all UBE2K Antibodies
    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
    Binding Specificity
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-139
    Reactivity
    • 45
    • 20
    • 18
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Mouse
    Host
    • 42
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 45
    • 2
    Polyclonal
    Conjugate
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2K antibody is un-conjugated
    Application
    • 36
    • 26
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2.
    Clone
    RB4144
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Furukawa, Kubo, Kikuchi, Tokura, Fujita, Sakurabayashi: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).

    Kikuchi, Furukawa, Kubo, Tokura, Hayashi, Nakamura, Matsuda, Sakurabayashi: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).

    Petersén, Mani, Brundin: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).

  • Target
    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
    Alternative Name
    HIP2 (UBE2K Products)
    Synonyms
    E2-25K antibody, HIP2 antibody, HYPG antibody, LIG antibody, UBC1 antibody, E2-25k antibody, Hip2 antibody, Hypg antibody, Lig antibody, e2-25k antibody, hip2 antibody, hypg antibody, lig antibody, AW492011 antibody, D5Ertd601e antibody, ube2k antibody, zgc:103472 antibody, zgc:110791 antibody, ubiquitin conjugating enzyme E2 K antibody, ubiquitin-conjugating enzyme E2K antibody, ubiquitin conjugating enzyme E2 K S homeolog antibody, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) antibody, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) antibody, UBE2K antibody, Ube2k antibody, ube2k.S antibody, ube2k antibody, ube2kb antibody, ube2ka antibody
    Background
    HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
    Molecular Weight
    22407
    NCBI Accession
    NP_001104582, NP_001104583, NP_005330
    UniProt
    P61086
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