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VTI1B antibody (AA 1-206)

VTI1B Reactivity: Human, Mouse, Rat WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1742350
  • Target See all VTI1B Antibodies
    VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-206
    Reactivity
    • 39
    • 14
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 36
    • 2
    • 1
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VTI1B antibody is un-conjugated
    Application
    • 26
    • 22
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Specificity
    Specific for vti1b.
    Purification
    antiserum
    Immunogen
    Recombinant rat vti1b (aa 1-206).
    Top Product
    Discover our top product VTI1B Primary Antibody
  • Application Notes
    WB: 1 : 1000 (AP staining)
    ICC: 1 : 1000
    IHC-P: 1 : 250
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS
    Handling Advice
    Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
    Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.
    Storage
    4 °C/-20 °C
    Storage Comment
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Bhat, Friedmann, Knörck, Hoxha, Leidinger, Backes, Meese, Keller, Rettig, Hoth, Qu, Schwarz: "Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes." in: Biochimica et biophysica acta, Vol. 1863, Issue 7 Pt A, pp. 1653-64, (2016) (PubMed).

    Golebiewska, Harper, Williams, Savage, Goggs, Fischer von Mollard, Poole: "Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability." in: The Journal of biological chemistry, Vol. 290, Issue 3, pp. 1536-45, (2015) (PubMed).

    Ramirez, Khvotchev, Trauterman, Kavalali: "Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission." in: Neuron, Vol. 73, Issue 1, pp. 121-34, (2012) (PubMed).

    Offenhäuser, Lei, Roy, Collins, Stow, Murray: "Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 6, pp. 762-73, (2011) (PubMed).

    Qu, Pattu, Junker, Schwarz, Bhat, Kummerow, Marshall, Matti, Neumann, Pfreundschuh, Becherer, Rieger, Rettig, Hoth: "Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 12, pp. 6894-904, (2011) (PubMed).

    Fraldi, Annunziata, Lombardi, Kaiser, Medina, Spampanato, Fedele, Polishchuk, Sorrentino, Simons, Ballabio: "Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders." in: The EMBO journal, Vol. 29, Issue 21, pp. 3607-20, (2010) (PubMed).

  • Target
    VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))
    Alternative Name
    Vti1b (VTI1B Products)
    Synonyms
    VTI1 antibody, VTI1-LIKE antibody, VTI1L antibody, VTI2 antibody, v-SNARE antibody, vti1-rp1 antibody, AU015348 antibody, GES30 antibody, MVti1b antibody, SNARE antibody, Vti1-rp1 antibody, zgc:63525 antibody, VTI1B antibody, vesicle transport through interaction with t-SNAREs 1B antibody, vesicle transport through interaction with t-SNAREs 1B pseudogene antibody, VTI1B antibody, Vti1b antibody, vti1b antibody, LOC461624 antibody
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