Oct-2 antibody (AA 112-297)
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- Target See all Oct-2 (POU2F2) Antibodies
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
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Binding Specificity
- AA 112-297
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Oct-2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Staining Methods (StM), Coating (Coat)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
- Clone
- Oct2-2137
- Isotype
- IgG1 kappa
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anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 11-100) antibody
POU2F2 Reactivity: Human, Mouse WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) antibodyPOU2F2 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 112-297) antibodyPOU2F2 Reactivity: Human IHC, StM Host: Mouse Monoclonal Oct2-2136 unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 1-400) antibodyPOU2F2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 277-389) antibodyPOU2F2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 1-400) antibodyPOU2F2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3E3-6F9 unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 10-39), (N-Term) antibodyPOU2F2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33756 unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (C-Term) antibodyPOU2F2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IP, DB Host: Rabbit Polyclonal unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (N-Term) antibodyPOU2F2 Reactivity: Human, Mouse, Rat, Dog, Pig WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-POU domain, class 2, transcription factor 2 (POU2F2) (AA 10-39) antibodyPOU2F2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Positive Control: Raji or U-937 cells. Spleen or Tonsil.
Known Application: ELISA (For coating, order Ab without BSA)Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
- Alternative Name
- POU2F2 (POU2F2 Products)
- Synonyms
- OCT2 antibody, OTF2 antibody, Oct-2 antibody, Pou2f2 antibody, Oct2a antibody, Oct2b antibody, Otf-2 antibody, Otf2 antibody, 2-Oct antibody, Oct2 antibody, POU class 2 homeobox 2 antibody, POU domain, class 2, transcription factor 2 antibody, solute carrier family 22 (organic cation transporter), member 2 antibody, POU2F2 antibody, Pou2f2 antibody, SLC22A2 antibody
- Background
- Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
- Molecular Weight
- 60kDa
- Gene ID
- 5452
- UniProt
- P09086
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