UGT1A1 antibody (AA 1-200)
(1 reference)-
- Target See all UGT1A1 Antibodies
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
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Binding Specificity
- AA 1-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UGT1A1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- MAVESQGGRP LVLGLLLCVL GPVVSHAGKI LLIPVDGSHW LSMLGAIQQL QQRGHEIVVL APDASLYIRD GAFYTLKTYP VPFQREDVKE SFVSLGHNVF ENDSFLQRVI KTYKKIKKDS AMLLSGCSHL LHNKELMASL AESSFDVMLT DPFLPCSPIV AQYLSLPTVF FLHALPCSLE FEATQCPNPF SYVPRPLSSH
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UGT1A1 (NP_000454.1).
- Isotype
- IgG
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anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibody
UGT1A1 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 316-533) antibodyUGT1A1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 65-90), (N-Term) antibodyUGT1A1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB22607 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibodyUGT1A1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 395-482) antibodyUGT1A1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 54-159) antibodyUGT1A1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1C5 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 251-300) antibodyUGT1A1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 36-85) antibodyUGT1A1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Fenofibrate pre-treatment suppressed inflammation by activating phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling in renal ischemia-reperfusion injury." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 35, Issue 1, pp. 58-63, (2015) (PubMed).
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: "Fenofibrate pre-treatment suppressed inflammation by activating phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling in renal ischemia-reperfusion injury." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 35, Issue 1, pp. 58-63, (2015) (PubMed).
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- Target
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
- Alternative Name
- UGT1A1 (UGT1A1 Products)
- Synonyms
- BILIQTL1 antibody, GNT1 antibody, HUG-BR1 antibody, UDPGT antibody, UDPGT 1-1 antibody, UGT1 antibody, UGT1A antibody, Gnt1 antibody, UGT1A01 antibody, Udpgt-1a antibody, UgtBr1 antibody, Udpgt antibody, Ugt1 antibody, zgc:123097 antibody, UDP glucuronosyltransferase family 1 member A1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A1 antibody, UDP-glucuronosyltransferase 1-1 antibody, UDP-glucuronosyltransferase antibody, UDP-glucuronosyltransferase 1-6 antibody, UDP glucuronosyltransferase 1 family polypeptide a1 antibody, UGT1A1 antibody, Ugt1a1 antibody, LOC100065342 antibody, LOC100125517 antibody, LOC100229734 antibody, LOC100405984 antibody, LOC100511479 antibody, ugt1a1 antibody
- Background
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.,UGT1A1,BILIQTL1,GNT1,HUG-BR1,UDPGT,UDPGT 1-1,UGT1,UGT1A,UDPGT1-1,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A1
- Molecular Weight
- 49 kDa/59 kDa
- Gene ID
- 54658
- UniProt
- P22309
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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