EIF3I antibody (C-Term)
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- Target See all EIF3I Antibodies
- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EIF3I antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- EIF3I Antibody detects endogenous levels of total EIF3I.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human EIF3I, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product EIF3I Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (AA 276-486) antibody
EIF3I Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (AA 226-325) antibodyEIF3I Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3B10 unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (AA 1-323) antibodyEIF3I Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) antibodyEIF3I Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I) (C-Term) antibodyEIF3I Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow WB, IHC, IP Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
- Alternative Name
- EIF3I (EIF3I Products)
- Synonyms
- EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, 36kDa antibody, D4Ertd632e antibody, Eif3s2 antibody, Trip1 antibody, eIF-3-beta antibody, eIF3 p36 antibody, eif3s2 antibody, hm:zehn0464 antibody, wu:fb62b08 antibody, zgc:56211 antibody, zgc:77823 antibody, CaO19.2967 antibody, eIF-3 39 kDa subunit homolog antibody, eIF3i antibody, eif3-beta antibody, eif3-p36 antibody, eif3i antibody, pro2242 antibody, trip-1 antibody, trip1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit I antibody, Eukaryotic Initiation Factor antibody, Eukaryotic translation initiation factor 3 subunit I antibody, translation initiation factor eIF3 subunit i antibody, eukaryotic translation initiation factor 3 subunit I L homeolog antibody, EIF3I antibody, Eif3i antibody, eif-3.I antibody, eIF3i antibody, eif3i antibody, TIF34 antibody, eif3i.L antibody
- Background
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Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3I
- Molecular Weight
- 36 kDa
- Gene ID
- 8668
- UniProt
- Q13347
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
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