SYTL2 antibody
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- Target See all SYTL2 Antibodies
- SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SYTL2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse SYTL2/SLP2
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anti-Synaptotagmin Like Protein 2 (SYTL2) (AA 329-880) antibody
SYTL2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Synaptotagmin Like Protein 2 (SYTL2) (AA 840-868) antibodySYTL2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB23826 unconjugated
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- Application Notes
- IHC/IF (H,M,R) 1:800-1:1600/1:600-1:1200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
- Alternative Name
- SYTL2/SLP2 (SYTL2 Products)
- Synonyms
- AI266830 antibody, Slp2 antibody, Slp2-a antibody, Slp2-b antibody, Slp2-c antibody, Slp2-d antibody, mKIAA1597 antibody, CHR11SYT antibody, EXO4 antibody, SGA72M antibody, SLP2 antibody, SLP2A antibody, synaptotagmin-like 2 antibody, synaptotagmin like 2 antibody, Sytl2 antibody, SYTL2 antibody
- Background
- Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
- Gene ID
- 83671
- NCBI Accession
- NP_001035174
- UniProt
- Q99N50
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