CCDC109B antibody (Regulatory Subunit)
CCDC109B
Reactivity: Human
ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
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- Target See all CCDC109B Antibodies
- CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))
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Binding Specificity
- AA 89-219, Regulatory Subunit
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCDC109B antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))
- Alternative Name
- MCUB (CCDC109B Products)
- Synonyms
- 9030408N13Rik antibody, mitochondrial calcium uniporter dominant negative beta subunit antibody, MCUB antibody, Mcub antibody
- Background
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Background: Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Aliases: MCUB antibody, CCDC109BCalcium uniporter regulatory subunit MCUb antibody, mitochondrial antibody, MCUb antibody, Coiled-coil domain-containing protein 109B antibody
- UniProt
- Q9NWR8
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