JMJD2D antibody
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- Target See all JMJD2D (KDM4D) Antibodies
- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This JMJD2D antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human KDM4D
- Isotype
- IgG
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anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibody
KDM4D Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 337-499) antibodyKDM4D Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (N-Term) antibodyKDM4D Reactivity: Human, Rat ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 1-523) antibodyKDM4D Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 460-520) antibodyKDM4D Reactivity: Human, Monkey, Primate WB Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (C-Term) antibodyKDM4D Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 484-516), (C-Term) antibodyKDM4D Reactivity: Human WB Host: Rabbit Polyclonal RB10797 unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 434-483) antibodyKDM4D Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4D (KDM4D) (AA 484-516) antibodyKDM4D Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
- Alternative Name
- KDM4D (KDM4D Products)
- Synonyms
- JMJD2D antibody, 4932416A15 antibody, Jmjd2d antibody, KDM4D antibody, lysine demethylase 4D antibody, lysine-specific demethylase 4D antibody, lysine (K)-specific demethylase 4D antibody, KDM4D antibody, LOC524768 antibody, Kdm4d antibody, LOC617971 antibody, LOC100067461 antibody, LOC698455 antibody, LOC100514356 antibody
- Background
- JMJD2D (Jumonji domain-containing protein 2D), also known as JHDM3D or KDM4D, is a 520 amino acid protein that belongs to the JHDM3 histone demethylase family. Localized to the nucleus, JMJD2D functions as a histone demethylase that removes specific methyl residues from Histone H3, thereby playing a crucial role in the histone code. JMJD2D binds iron as a cofactor and contains one JMJC domain and one JMJN domain, both of which are thought to exhibit enzymatic activity during chromatin remodeling events. In addition, JMJD2D forms a complex with the ligand-bound form of the androgen receptor (AR) and, through this interaction, activates AR expression. Overexpression of AR is associated with prostate cancer, suggesting that, via its ability to upregulate AR, JMJD2D may be involved in carcinogenesis.
- Molecular Weight
- 59 kDa
- UniProt
- Q6B0I6
- Pathways
- Warburg Effect
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