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MBNL3 antibody (AA 116-211)

MBNL3 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7160361
  • Target See all MBNL3 Antibodies
    MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 116-211
    Reactivity
    • 29
    • 2
    Human
    Host
    • 28
    • 2
    Rabbit
    Clonality
    • 29
    • 1
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBNL3 antibody is un-conjugated
    Application
    • 19
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Muscleblind-like protein 3 protein (116-211AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))
    Alternative Name
    MBNL3 (MBNL3 Products)
    Synonyms
    A530038J18Rik antibody, AI661274 antibody, CHCR antibody, E430034C16Rik antibody, MBLX antibody, MBLX39 antibody, MBXL antibody, mbxl antibody, RGD1565834 antibody, muscleblind like splicing regulator 3 antibody, muscleblind like splicing factor 3 antibody, Muscleblind-like protein 3-like antibody, muscleblind-like splicing regulator 3 antibody, MBNL3 antibody, Mbnl3 antibody, mbnl3 antibody
    Background

    Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

    Aliases: A530038J18Rik antibody, AI661274 antibody, CHCR antibody, Cys3His CCG1 required protein antibody, Cys3His CCG1-required protein antibody, E430034C16Rik antibody, MBLX antibody, MBLX39 antibody, MBNL 3 antibody, Mbnl3 antibody, MBNL3_HUMAN antibody, MBXL antibody, Muscleblind like 3 antibody, Muscleblind like protein 3 antibody, Muscleblind like splicing regulator 3 antibody, Muscleblind like X linked protein antibody, Muscleblind-like protein 3 antibody, Muscleblind-like X-linked protein antibody, OTTMUSP00000019072 antibody, OTTMUSP00000019073 antibody, OTTMUSP00000019074 antibody, Protein HCHCR antibody, RP23-98P13.1 antibody

    UniProt
    Q9NUK0
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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