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PKN1 antibody (AA 442-620)

PKN1 Reactivity: Human WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 4H10B1 unconjugated
Catalog No. ABIN5542353
  • Target See all PKN1 Antibodies
    PKN1 (Protein Kinase N1 (PKN1))
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-620
    Reactivity
    • 32
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 22
    • 11
    Mouse
    Clonality
    • 24
    • 9
    Monoclonal
    Conjugate
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKN1 antibody is un-conjugated
    Application
    • 18
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. coli.
    Clone
    4H10B1
    Isotype
    IgG2b
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    PKN1 (Protein Kinase N1 (PKN1))
    Alternative Name
    PKN1 (PKN1 Products)
    Synonyms
    DBK antibody, PAK-1 antibody, PAK1 antibody, PKN antibody, PKN-ALPHA antibody, PRK1 antibody, PRKCL1 antibody, F730027O18Rik antibody, Pkn antibody, Prkcl1 antibody, Stk3 antibody, PKN1 antibody, 3-2 antibody, CG2049 antibody, CG2055 antibody, CT6637 antibody, CT6660 antibody, DPKN antibody, Dmel\\CG2049 antibody, Dpkn antibody, PRK2 antibody, Pk45C antibody, Pk?3 antibody, dPKN antibody, l(2)06736 antibody, l(2)45Ca antibody, v(2)rG232 antibody, protein kinase N1 antibody, protein kinase N1b antibody, Protein kinase N antibody, PKN1 antibody, Pkn1 antibody, pkn1b antibody, pkn1 antibody, Pkn antibody
    Background

    Description: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Aliases: DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA

    Molecular Weight
    104 kDa
    Gene ID
    5585
    HGNC
    5585
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