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Mesp2 antibody (AA 37-94)

Mesp2 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 1B3F9 unconjugated
Catalog No. ABIN1098148
  • Target See all Mesp2 Antibodies
    Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-94
    Reactivity
    • 4
    • 4
    • 2
    Human
    Host
    • 6
    • 1
    Mouse
    Clonality
    • 6
    • 1
    Monoclonal
    Conjugate
    • 7
    This Mesp2 antibody is un-conjugated
    Application
    • 5
    • 4
    • 1
    ELISA, Western Blotting (WB)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MESP2 (AA: 37-94 ) expressed in E. coli.
    Clone
    1B3F9
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: "Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis." in: Studies in health technology and informatics, Vol. 176, pp. 52-5, (2012) (PubMed).

    Cornier, Staehling-Hampton, Delventhal, Saga, Caubet, Sasaki, Ellard, Young, Ramirez, Carlo, Torres, Emans, Turnpenny, Pourquié: "Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1334-41, (2008) (PubMed).

  • Target
    Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))
    Alternative Name
    MESP2 (Mesp2 Products)
    Synonyms
    bHLHc6 antibody, SCDO2 antibody, mesoderm posterior 2 antibody, mesoderm posterior bHLH transcription factor 2 antibody, Mesp2 antibody, MESP2 antibody
    Background

    Description: This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). , ,

    Aliases: SCDO2, bHLHc6

    Molecular Weight
    41.8 kDa
    Gene ID
    145873
    HGNC
    145873
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