MBTPS1 antibody (Internal Region)
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- Target See all MBTPS1 Antibodies
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MBTPS1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MBTPS1 Antibody detects endogenous levels of total MBTPS1.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MBTPS1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MBTPS1 Primary Antibody
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anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) antibody
MBTPS1 Reactivity: Human IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 17-70) antibodyMBTPS1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 803-1052) antibodyMBTPS1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 246-355) antibodyMBTPS1 Reactivity: Human ELISA, IF Host: Mouse Monoclonal 2E6 unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) antibodyMBTPS1 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (C-Term) antibodyMBTPS1 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 187-400) antibodyMBTPS1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 187-400) antibodyMBTPS1 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 803-1052) antibodyMBTPS1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
- Alternative Name
- MBTPS1 (MBTPS1 Products)
- Synonyms
- PCSK8 antibody, S1P antibody, SKI-1 antibody, 0610038M03Rik antibody, AV003995 antibody, Ski1 antibody, mKIAA0091 antibody, S1p antibody, Ski-1 antibody, membrane bound transcription factor peptidase, site 1 antibody, membrane-bound transcription factor peptidase, site 1 antibody, MBTPS1 antibody, Mbtps1 antibody
- Background
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Description: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.
Gene: MBTPS1
- Molecular Weight
- 117 kDa
- Gene ID
- 8720
- UniProt
- Q14703
- Pathways
- ER-Nucleus Signaling
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