DIABLO antibody (C-Term)
(1 reference)-
- Target See all DIABLO Antibodies
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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Binding Specificity
- AA 211-239, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DIABLO antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This SMAC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the C-terminal region of human SMAC.
- Clone
- RB20755
- Isotype
- Ig Fraction
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anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibody
DIABLO Reactivity: Human WB, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO Reactivity: Human, Monkey WB, IHC (p) Host: Mouse Monoclonal 79-1-83 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibodyDIABLO Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibodyDIABLO Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 222-237) antibodyDIABLO Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239) antibodyDIABLO Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibodyDIABLO Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibodyDIABLO Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibodyDIABLO Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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-
: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).
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: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).
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- Target
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- Alternative Name
- SMAC (DIABLO Products)
- Synonyms
- smac antibody, smac3 antibody, diablo-s antibody, 0610041G12Rik antibody, 1700006L01Rik antibody, AU040403 antibody, Smac antibody, DFNA64 antibody, SMAC antibody, DBO antibody, XSmac antibody, diablo, IAP-binding mitochondrial protein antibody, diablo IAP-binding mitochondrial protein antibody, diablo, IAP-binding mitochondrial protein L homeolog antibody, diablo antibody, Diablo antibody, DIABLO antibody, diablo.L antibody
- Background
- SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs.
- Molecular Weight
- 27131
- NCBI Accession
- NP_001265231, NP_001265232, NP_001265233, NP_001265271, NP_063940, NP_620308
- UniProt
- Q9NR28
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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