Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

BCCIP antibody (AA 1-314)

BCCIP Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6137485
  • Target See all BCCIP Antibodies
    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
    Binding Specificity
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-314
    Reactivity
    • 34
    • 2
    • 2
    Human
    Host
    • 29
    • 5
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCCIP antibody is un-conjugated
    Application
    • 15
    • 14
    • 13
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MASRSKRRAV ESGVPQPPDP PVQRDEEEEK EVENEDEDDD DSDKEKDEED EVIDEEVNIE FEAYSLSDND YDGIKKLLQQ LFLKAPVNTA ELTDLLIQQN HIGSVIKQTD VSEDSNDDMD EDEVFGFISL LNLTERKGTQ CVEQIQELVL RFCEKNCEKS MVEQLDKFLN DTTKPVGLLL SERFINVPPQ IALPMYQQLQ KELAGAHRTN KPCGKCYFYL LISKTFVEAG KNNSKKKPSN KKKAALMFAN AEEEFFYEKA ILKFNYSVQE ESDTCLGGKW SFDDVPMTPL RTVMLIPGDK MNEIMDKLKE YLSV
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-314 of human BCCIP (NP_510868.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
    Alternative Name
    BCCIP (BCCIP Products)
    Synonyms
    zgc:110272 antibody, mp:zf637-1-000774 antibody, BCCIP antibody, DKFZp459K2416 antibody, MGC82792 antibody, tok-1 antibody, MGC89311 antibody, TOK-1 antibody, TOK1 antibody, 1110013J05Rik antibody, BRCA2 and CDKN1A interacting protein antibody, BRCA2 and CDKN1A interacting protein L homeolog antibody, BCCIP antibody, bccip antibody, bccip.L antibody, Bccip antibody
    Background
    This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.,BCCIP,TOK-1,TOK1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Immunology & Inflammation,Cytokines,BCCIP
    Molecular Weight
    33 kDa/35 kDa/36 kDa
    Gene ID
    56647
    UniProt
    Q9P287
You are here:
Support