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Cyclin L1 antibody (C-Term)

CCNL1 Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261157
  • Target See all Cyclin L1 (CCNL1) Antibodies
    Cyclin L1 (CCNL1)
    Binding Specificity
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 26
    • 17
    • 17
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 24
    • 3
    Rabbit
    Clonality
    • 24
    • 3
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cyclin L1 antibody is un-conjugated
    Application
    • 17
    • 10
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Cyclin L1 Antibody detects endogenous levels of total Cyclin L1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Cyclin L1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Cyclin L1 (CCNL1)
    Alternative Name
    CCNL1 (CCNL1 Products)
    Synonyms
    ANIA6A antibody, PRO1073 antibody, ania-6a antibody, 2610030E23Rik antibody, AU018493 antibody, Ccnl antibody, Ania-6a antibody, ccnl1 antibody, fd99b09 antibody, wu:fd99b09 antibody, zgc:55544 antibody, MCM2 antibody, cyclin-L1 antibody, MGC132032 antibody, bm-001 antibody, pro1073 antibody, MGC108436 antibody, Ccnl1 antibody, cyclin L1 antibody, cyclin L1b antibody, cyclin-L1 antibody, cyclin L1 L homeolog antibody, cyclin L1 S homeolog antibody, CCNL1 antibody, Ccnl1 antibody, ccnl1b antibody, LOC485730 antibody, ccnl1.L antibody, ccnl1 antibody, LOC100136245 antibody, ccnl1.S antibody
    Background

    Description: Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018). Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906). May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).

    Gene: CCNL1

    Molecular Weight
    60kDa
    Gene ID
    57018
    UniProt
    Q9UK58
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