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BIRC6 antibody (AA 4810-4844)

BIRC6 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB56699 unconjugated
Catalog No. ABIN6243063
  • Target See all BIRC6 Antibodies
    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
    Binding Specificity
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4810-4844
    Reactivity
    • 24
    • 3
    • 1
    Human
    Host
    • 21
    • 2
    • 1
    Rabbit
    Clonality
    • 23
    • 1
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIRC6 antibody is un-conjugated
    Application
    • 12
    • 12
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.
    Clone
    RB56699
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
    Alternative Name
    BIRC6 (BIRC6 Products)
    Synonyms
    APOLLON antibody, BRUCE antibody, bruce antibody, apollon antibody, BIRC6 antibody, A430032G04Rik antibody, A430040A19Rik antibody, AA501170 antibody, Bruce antibody, D630005A10Rik antibody, mKIAA1289 antibody, baculoviral IAP repeat containing 6 antibody, baculoviral IAP repeat-containing 6 antibody, BIRC6 antibody, Birc6 antibody, birc6 antibody
    Background
    Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.
    Molecular Weight
    530255
    UniProt
    Q9NR09
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