ALS2 antibody (AA 1-280)
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- Target See all ALS2 Antibodies
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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Binding Specificity
- AA 1-280
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ALS2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- MDSKKRSSTE AEGSKERGLV HIWQAGSFPI TPERLPGWGG KTVLQAALGV KHGVLLTEDG EVYSFGTLPW RSGPVEICPS SPILENALVG QYVITVATGS FHSGAVTDNG VAYMWGENSA GQCAVANQQY VPEPNPVSIA DSEASPLLAV RILQLACGEE HTLALSISRE IWAWGTGCQL GLITTAFPVT KPQKVEHLAG RVVLQVACGA FHSLALVQCL PSQDLKPVPE RCNQCSQLLI TMTDKEDHVI ISDSHCCPLG VTLTESQAEN HASTALSPST
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALS2 (NP_065970.2).
- Isotype
- IgG
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anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibody
ALS2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1248-1277), (C-Term) antibodyALS2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB18853 unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 221-320) antibodyALS2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4F10 unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) antibodyALS2 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (N-Term) antibodyALS2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (C-Term) antibodyVerified ALS2 Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 221-321) antibodyALS2 Reactivity: Mouse WB Host: Mouse Monoclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1007-1056) antibodyALS2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Bat, Chicken, Monkey WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
- Alternative Name
- ALS2 (ALS2 Products)
- Background
- The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.,ALS2,ALS2CR6,ALSJ,IAHSP,PLSJ,alsin,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,ALS2
- Molecular Weight
- 42 kDa/86 kDa/183 kDa
- Gene ID
- 57679
- UniProt
- Q96Q42
- Pathways
- Skeletal Muscle Fiber Development
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