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PTPRE antibody

PTPRE Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7167503
  • Target See all PTPRE Antibodies
    PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
    Reactivity
    • 48
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 4
    Rabbit
    Clonality
    • 45
    • 3
    Polyclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPRE antibody is un-conjugated
    Application
    • 35
    • 26
    • 20
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Receptor-type tyrosine-protein phosphatase epsilon protein
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
    Alternative Name
    PTPRE (PTPRE Products)
    Synonyms
    ptpra antibody, HPTPE antibody, PTPE antibody, R-PTP-EPSILON antibody, PTPe antibody, PTPepsilon antibody, RPTPepsilon antibody, protein tyrosine phosphatase, receptor type E L homeolog antibody, protein tyrosine phosphatase, receptor type E antibody, protein tyrosine phosphatase, receptor type, E antibody, ptpre.L antibody, PTPRE antibody, Ptpre antibody
    Background

    Background: Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake.Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca2+.

    Aliases: DKFZp313F1310 antibody, FLJ57799 antibody, FLJ58245 antibody, HPTPE antibody, Protein tyrosine phosphatase epsilon antibody, Protein tyrosine phosphatase receptor type E antibody, Protein tyrosine phosphatase receptor type epsilon antibody, Protein tyrosine phosphatase receptor type epsilon polypeptide antibody, Protein-tyrosine phosphatase epsilon antibody, PTPE antibody, Ptpre antibody, PTPRE_HUMAN antibody, R PTP Epsilon antibody, R-PTP-epsilon antibody, Receptor-type tyrosine-protein phosphatase epsilon antibody

    UniProt
    P23469
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