SH3KBP1 antibody (N-Term)
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- Target See all SH3KBP1 Antibodies
- SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SH3KBP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- CIN85 Antibody detects endogenous levels of total CIN85.
- Predicted Reactivity
- Pig,Zebrafish,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CIN85, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) antibody
SH3KBP1 Reactivity: Human, Mouse, Rat IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (AA 224-308) antibodySH3KBP1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1F11 unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (AA 1-665) antibodySH3KBP1 Reactivity: Human WB, IHC (p) Host: Mouse Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) antibodySH3KBP1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (AA 107-156) antibodySH3KBP1 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Cow, Horse, Pig, Bat WB Host: Rabbit Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (N-Term) antibodySH3KBP1 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))
- Alternative Name
- SH3KBP1 (SH3KBP1 Products)
- Synonyms
- CD2BP3 antibody, CIN85 antibody, GIG10 antibody, HSB-1 antibody, HSB1 antibody, MIG18 antibody, 1200007H22Rik antibody, 1700125L08Rik antibody, 5830464D22Rik antibody, AI447724 antibody, IN85 antibody, Ruk antibody, Seta antibody, SH3 domain containing kinase binding protein 1 antibody, SH3-domain kinase binding protein 1 antibody, SH3 domain-containing kinase-binding protein 1 antibody, SH3KBP1 antibody, sh3kbp1 antibody, LOC100551401 antibody, Sh3kbp1 antibody
- Background
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Description: Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins. The association with CBL, and thus the receptor internalization, may inhibited by an interaction with PDCD6IP and/or SPRY2. Involved in regulation of ligand-dependent endocytosis of the IgE receptor. Attenuates phosphatidylinositol 3-kinase activity by interaction with its regulatory subunit (By similarity). May be involved in regulation of cell adhesion, promotes the interaction between TTK2B and PDCD6IP. May be involved in the regulation of cellular stress response via the MAPK pathways through its interaction with MAP3K4. Is involved in modulation of tumor necrosis factor mediated apoptosis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration.
Gene: SH3KBP1
- Molecular Weight
- 85 kDa
- Gene ID
- 30011
- UniProt
- Q96B97
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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