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NLRC4 antibody

NLRC4 Reactivity: Human, Mouse IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7008065
  • Target See all NLRC4 Antibodies
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    Reactivity
    • 38
    • 14
    • 6
    • 2
    Human, Mouse
    Host
    • 27
    • 9
    • 2
    Rabbit
    Clonality
    • 28
    • 10
    Polyclonal
    Conjugate
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRC4 antibody is un-conjugated
    Application
    • 28
    • 17
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of mouse NLRC4 (NP_001028539.1).
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    Alternative Name
    NLRC4 (NLRC4 Products)
    Synonyms
    CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
    Background
    This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
    Gene ID
    268973
    UniProt
    Q9NPP4
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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