BBS4 antibody (AA 350-519)
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- Target See all BBS4 Antibodies
- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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Binding Specificity
- AA 350-519
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BBS4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Bardet-Biedl syndrome 4 protein (350-519AA)
- Isotype
- IgG
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anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-240) antibody
BBS4 Reactivity: Human, Mouse, Rat WB Host: Mouse Monoclonal 1292CT845-130-218 unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 431-519) antibodyBBS4 Reactivity: Mouse WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 337-369) antibodyBBS4 Reactivity: Human WB Host: Rabbit Polyclonal RB14682 unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (N-Term) antibodyBBS4 Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 33-46) antibodyVerified BBS4 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 125-139) antibodyVerified BBS4 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 215-264) antibodyBBS4 Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Zebrafish (Danio rerio), Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 71-120) antibodyBBS4 Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
- Alternative Name
- BBS4 (BBS4 Products)
- Synonyms
- CG13232 antibody, Dmel\\CG13232 antibody, zgc:152964 antibody, AW537059 antibody, AW742241 antibody, D9Ertd464e antibody, Bardet-Biedl syndrome 4 antibody, bardet-biedl syndrome 4 antibody, Bardet-Biedl syndrome 4 (human) antibody, BBS4 antibody, bbs4 antibody, Bbs4 antibody
- Background
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Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.
Aliases: Bardet Biedl syndrome 4 protein antibody, Bardet-Biedl syndrome 4 protein antibody, Bbs4 antibody, BBS4_HUMAN antibody
- UniProt
- Q96RK4
- Pathways
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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