PIAS4 antibody (C-Term)
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- Target See all PIAS4 Antibodies
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PIAS4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- PIAS4 Antibody detects endogenous levels of total PIAS4.
- Predicted Reactivity
- Pig,Bovine,Sheep,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PIAS4, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 48-79), (N-Term) antibody
PIAS4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB0680 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 471-499), (C-Term) antibodyPIAS4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB00682 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 46-60) antibodyPIAS4 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 66-241) antibodyPIAS4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 44-73), (N-Term) antibodyPIAS4 Reactivity: Mouse WB Host: Rabbit Polyclonal RB33956 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 44-60) antibodyPIAS4 Reactivity: Human, Monkey WB, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 1-510) antibodyPIAS4 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (N-Term) antibodyPIAS4 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Monkey, Bat, Chicken, Pig, Xenopus laevis, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibodyPIAS4 Reactivity: Human, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 451-500) antibodyPIAS4 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
- Alternative Name
- PIAS4 (PIAS4 Products)
- Synonyms
- PIASY antibody, Piasg antibody, ZMIZ6 antibody, pias4 antibody, piasy antibody, wu:fc54c11 antibody, wu:fi18c10 antibody, wu:fi20e09 antibody, wu:fk93f11 antibody, zgc:66410 antibody, piasg antibody, zmiz6 antibody, LOC100219439 antibody, Pias-gamma antibody, pias4l antibody, wu:fi26h11 antibody, zgc:63923 antibody, protein inhibitor of activated STAT 4 antibody, protein inhibitor of activated STAT, 4 antibody, protein inhibitor of activated STAT, 4a antibody, protein inhibitor of activated STAT 4 L homeolog antibody, protein inhibitor of activated STAT, 4b antibody, PIAS4 antibody, Pias4 antibody, pias4a antibody, pias4.L antibody, pias4 antibody, pias4b antibody
- Background
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Description: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
Gene: PIAS4
- Molecular Weight
- 57 kDa
- Gene ID
- 51588
- UniProt
- Q8N2W9
- Pathways
- JAK-STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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