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TRPV4 antibody (Middle Region)

Name: TRPV4 antibody (Middle Region)
SKU: ABIN2776284
Price: 472.77 USD
Availability: InStock

TRPV4 Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated

WB Suggested Anti-TRPV4 Antibody Titration: 0.

Immunohistochemistry (IHC) image for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Middle Region) antibody (ABIN2776284)

IHC

Host: Rabbit Target Name: TRPV4 Sample Type: HT1080 Antibody Dilution: 1.

Host: Rabbit Target Name: TRPV4 Sample Type: PANC1 Antibody Dilution: 1.

IHC

5 images

(1 reference)

Catalog No. ABIN2776284

Datasheet as PDF

Target See all TRPV4 Antibodies

TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
Binding Specificity
16

14

9

5

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Middle Region
Reactivity
61

25

24

21

5

4

3

2

2

1

1

1

1
Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Guinea Pig
Host
61

2

1

1
Rabbit
Compatible Secondaries
Clonality
64

1
Polyclonal
Conjugate
31

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1
This TRPV4 antibody is un-conjugated
Application
50

25

17

13

7

6

3

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequence

RVDEVNWSHW NQNLGIINED PGKNETYQYY GFSHTVGRLR RDRWSSVVPR

Predicted Reactivity

Cow: 93%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%

Characteristics

This is a rabbit polyclonal antibody against TRPV4. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRPV4
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (3rd Extracellular Loop), (AA 647-662) antibody
TRPV4 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC, LCI Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Internal Region) antibody
TRPV4 Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Hamster, Horse WB, IHC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 853-871), (C-Term), (Intracellular) antibody
TRPV4 Reactivity: Human, Mouse, Rat WB, IHC, FACS, IF, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 1-230) antibody
TRPV4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 301-400) antibody
TRPV4 Reactivity: Human, Cow WB, ELISA, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (C-Term) antibody
TRPV4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) antibody
TRPV4 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (N-Term) antibody
TRPV4 Reactivity: Human, Mouse, Rat, Cow, Pig, Dog WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 461-510) antibody
TRPV4 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Internal Region) antibody
TRPV4 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilutions should be determined experimentally by the investigator.

Comment

Antigen size: 811 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Sampat, Dermksian, Oungoulian, Winchester, Bulinski, Ateshian, Hung: "Applied osmotic loading for promoting development of engineered cartilage." in: Journal of biomechanics, Vol. 46, Issue 15, pp. 2674-81, (2013) (PubMed).
Target

TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))

Alternative Name

TRPV4 (TRPV4 Products)

Background

TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. TRPV4 is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure.This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: OTRPC4, TRP12, VR-OAC, VRL-2, VRL2, VROAC, CMT2C, SPSMA, HMSN2C, SSQTL1
Protein Interaction Partner: UBC, ARRB2, KRIT1, ITCH, PACSIN3, PACSIN1, TRPV4, PACSIN2, MAP7, SRC, LYN, YES1, LCK, HCK, FYN, CALM1, OS9, PACS1,
Protein Size: 811

Molecular Weight

91 kDa

Gene ID

59341

NCBI Accession

NM_147204, NP_671737

Pathways

Hormone Transport, Cell-Cell Junction Organization