RFX3 antibody (C-Term)
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- Target See all RFX3 Antibodies
- RFX3 (Regulatory Factor X 3 (RFX3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RFX3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- RFX3 Antibody detects endogenous levels of total RFX3.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RFX3, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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anti-Regulatory Factor X 3 (RFX3) (AA 1-749) antibody
RFX3 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Regulatory Factor X 3 (RFX3) (C-Term) antibodyRFX3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X 3 (RFX3) (C-Term) antibodyRFX3 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X 3 (RFX3) (AA 661-690), (C-Term) antibodyRFX3 Reactivity: Human WB Host: Rabbit Polyclonal RB32572 unconjugated
anti-Regulatory Factor X 3 (RFX3) (Internal Region) antibodyRFX3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X 3 (RFX3) antibodyRFX3 Reactivity: Human WB Host: Mouse Monoclonal 3F7 unconjugated
anti-Regulatory Factor X 3 (RFX3) (AA 280-430) antibodyRFX3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X 3 (RFX3) (C-Term) antibodyRFX3 Reactivity: Human, Mouse, Rat, Monkey WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Regulatory Factor X 3 (RFX3) (AA 641-690) antibodyRFX3 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- RFX3 (Regulatory Factor X 3 (RFX3))
- Alternative Name
- RFX3 (RFX3 Products)
- Synonyms
- ba32f11.1 antibody, C230093O12Rik antibody, MRFX3 antibody, zgc:153245 antibody, regulatory factor X3 antibody, regulatory factor X, 3 (influences HLA class II expression) antibody, Rfx3 antibody, rfx3 antibody, RFX3 antibody
- Background
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Description: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5) (By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes (PubMed:20148032). Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells (PubMed:12411430).
Gene: RFX3
- Molecular Weight
- 84kDa
- Gene ID
- 5991
- UniProt
- P48380
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