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GRK1 antibody (AA 1-160)

GRK1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6134352
  • Target See all GRK1 Antibodies
    GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))
    Binding Specificity
    • 10
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-160
    Reactivity
    • 49
    • 41
    • 32
    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 2
    • 1
    Rabbit
    Clonality
    • 48
    • 2
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRK1 antibody is un-conjugated
    Application
    • 41
    • 25
    • 20
    • 5
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MDFGSLETVV ANSAFIAARG SFDGSSSQPS RDKKYLAKLK LPPLSKCESL RDSLSLEFES VCLEQPIGKK LFQQFLQSAE KHLPALELWK DIEDYDTADN DLQPQKAQTI LAQYLDPQAK LFCSFLDEGI VAKFKEGPVE IQDGLFQPLL QATLAHLGQA
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human GRK1 (NP_002920.1).
    Isotype
    IgG
  • Application Notes
    WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Liu, Chen, Yu, Raghupathy, Liu, Qin, Li, Huang, Liao, Wang, Zou, Shu, Tang, Liu: "Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish." in: Human molecular genetics, Vol. 24, Issue 16, pp. 4648-59, (2015) (PubMed).

  • Target
    GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))
    Alternative Name
    GRK1 (GRK1 Products)
    Synonyms
    GPRK1 antibody, RHOK antibody, RK antibody, Gprk1 antibody, Rhok antibody, Rk antibody, CG40129 antibody, CT4320 antibody, Dmel\\CG40129 antibody, Gprk-1 antibody, Rok antibody, gprk1 antibody, grk1 antibody, zgc:112194 antibody, G protein-coupled receptor kinase 1 antibody, G protein-coupled receptor kinase 1 a antibody, G protein-coupled receptor kinase 1 b antibody, GRK1 antibody, Grk1 antibody, Gprk1 antibody, grk1a antibody, grk1b antibody
    Background
    This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).,GRK1,GPRK1,RHOK,RK,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Tyrosine kinases,Neuroscience,GRK1
    Molecular Weight
    63 kDa
    Gene ID
    6011
    UniProt
    Q15835
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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