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ELAC2 antibody

ELAC2 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7263113
  • Target See all ELAC2 Antibodies
    ELAC2 (ElaC Homolog 2 (ELAC2))
    Reactivity
    • 31
    • 5
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 4
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELAC2 antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ELAC2 (NP_776065.1).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ELAC2 (ElaC Homolog 2 (ELAC2))
    Alternative Name
    ELAC2 (ELAC2 Products)
    Synonyms
    1110017O07Rik antibody, D11Wsu80e antibody, Hpc2 antibody, ELC2 antibody, HPC2 antibody, elaC ribonuclease Z 2 antibody, ELAC2 antibody, Elac2 antibody
    Background
    The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 105 kDa

    Calculated_MW: 50 kDa/56 kDa/87 kDa/92 kDa

    Gene ID
    60528
    UniProt
    Q9BQ52
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