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IL1RN antibody (Internal Region)

IL1RN Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262550
  • Target See all IL1RN Antibodies
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Binding Specificity
    • 28
    • 16
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 77
    • 33
    • 15
    • 9
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    Human, Mouse, Rat
    Host
    • 95
    • 33
    • 5
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 102
    • 36
    Polyclonal
    Conjugate
    • 68
    • 28
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1RN antibody is un-conjugated
    Application
    • 114
    • 51
    • 36
    • 25
    • 23
    • 21
    • 18
    • 18
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    IL1RN Antibody detects endogenous levels of total IL1RN.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IL1RN, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IL1RN Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Alternative Name
    IL1RN (IL1RN Products)
    Synonyms
    DIRA antibody, ICIL-1RA antibody, IL-1RN antibody, IL-1ra antibody, IL-1ra3 antibody, IL1F3 antibody, IL1RA antibody, IRAP antibody, MVCD4 antibody, IRAP1 antibody, IL1RN antibody, IL-1RA antibody, F630041P17Rik antibody, interleukin 1 receptor antagonist antibody, interleukin 1 receptor antagonist-like antibody, IL1RN antibody, Il1rn antibody, IL1RNL antibody
    Background

    Description: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

    Gene: IL1RN

    Molecular Weight
    20kDa
    Gene ID
    3557
    UniProt
    P18510
    Pathways
    NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
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