Arrestin 3 antibody (Middle Region)
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- Target See all Arrestin 3 (ARRB2) Antibodies
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Pig, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Arrestin 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- RLVIRKVQFA PEKPGPQPSA ETTRHFLMSD RSLHLEASLD KELYYHGEPL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against ARRB2. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ARRB2
- Top Product
- Discover our top product ARRB2 Primary Antibody
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anti-Arrestin, beta 2 (ARRB2) (Internal Region) antibody
Verified ARRB2 Reactivity: Human WB, ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4D2 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-400) antibodyARRB2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) antibodyARRB2 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 222-369) antibodyARRB2 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (C-Term) antibodyARRB2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibodyARRB2 Reactivity: Human WB, IHC, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 262-430) antibodyARRB2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 251-418) antibodyARRB2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 409 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
- Alternative Name
- ARRB2 (ARRB2 Products)
- Synonyms
- ARRB2 antibody, arb2 antibody, arr2 antibody, arrestin antibody, barr2 antibody, betaarr2 antibody, ARB2 antibody, ARR2 antibody, BARR2 antibody, BARRES antibody, AI326910 antibody, AW122872 antibody, arrb2 antibody, zgc:64007 antibody, arrestin beta 2 antibody, arrestin, beta 2 antibody, arrestin beta 2 L homeolog antibody, arrestin, beta 2b antibody, ARRB2 antibody, arrb2 antibody, Arrb2 antibody, arrb2.L antibody, arrb2b antibody
- Background
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Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: ARB2, ARR2, DKFZp686L0365, BARR2
Protein Interaction Partner: UBC, SRC, MAPK9, INSR, AKT1, USP33, ADRB2, TBXA2R, CYTH1, PTGDS, BAI1, LIMK1, CFL1, CSK, AGTR1, MAP2K4, MAPK10, MAP3K5, GCG, NFKBIA, MDM2, IGF1R, CLTC, ADRB1, HIPK3, EDNRA, gag-pol, ARRDC3, ARRDC4, SIRT1, PDE4D, Mlnr, Trhr, C5AR1, SLC9A5, AP2M1, HCRTR1, F
Protein Size: 409 - Molecular Weight
- 46 kDa
- Gene ID
- 409
- NCBI Accession
- NM_199004, NP_945355
- UniProt
- P32121
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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