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RPL5 antibody

RPL5 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855187
  • Target See all RPL5 Antibodies
    RPL5 (Ribosomal Protein L5 (RPL5))
    Reactivity
    • 49
    • 19
    • 18
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 49
    Rabbit
    Clonality
    • 49
    Polyclonal
    Conjugate
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RPL5 antibody is un-conjugated
    Application
    • 32
    • 24
    • 23
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to RPL5 (ribosomal protein L5)
    RPL5 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RPL5. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse brain , Rat2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chiang, Sparrer, van Gent, Lässig, Huang, Osterrieder, Hopfner, Gack: "Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity." in: Nature immunology, Vol. 19, Issue 1, pp. 53-62, (2017) (PubMed).

  • Target
    RPL5 (Ribosomal Protein L5 (RPL5))
    Alternative Name
    ribosomal protein L5 (RPL5 Products)
    Synonyms
    DBA6 antibody, L5 antibody, U21RNA antibody, CG17489 antibody, Dmel\\CG17489 antibody, E-2d antibody, M(2)40B antibody, Rp L5 antibody, Rpl5 antibody, dRPL5 antibody, yip6 antibody, rpl5 antibody, wu:fj02g05 antibody, zgc:86854 antibody, mg:cb01f08 antibody, rpl5l antibody, zgc:56511 antibody, zgc:77176 antibody, ribosomal protein L5 antibody, 60S ribosomal protein L5 antibody, Ribosomal protein L5 antibody, ribosomal protein L5 L homeolog antibody, 50S ribosomal protein L5 antibody, ribosomal protein L5 S homeolog antibody, ribosomal protein L5b antibody, rpl5 antibody, ribosomal protein L5a antibody, Rpl5 antibody, RPL5 antibody, rpl-5 antibody, RpL5 antibody, rpl5.L antibody, rpl5 antibody, rpl5.S antibody, rpl5b antibody, rpl5a antibody
    Background
    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

    Cellular Localization: Cytoplasm , Nucleus , nucleolus
    Molecular Weight
    34 kDa
    Gene ID
    6125
    UniProt
    P46777
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