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RPS6KB1 antibody (AA 1-352)

Name: RPS6KB1 antibody (AA 1-352)
Brand: antibodies-online
SKU: ABIN3023169
Price: 731.45 USD
Availability: InStock

RPS6KB1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using RPS6KB1 antibody.

Immunofluorescence analysis of NIH-3T3 cells using p70 S6 Kinase 1 1 Rabbit pAb (ABIN3023168, ABIN3023169, ABIN3023170, ABIN1513490 and ABIN6219422) at dilution of 1:100 (40x lens).

Immunohistochemistry (IHC) image for anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 1-352) antibody (ABIN3023169)

IHC

Immunohistochemistry of paraffin-embedded human breast cancer using p70 S6 Kinase 1 1 Rabbit pAb (ABIN3023168, ABIN3023169, ABIN3023170, ABIN1513490 and ABIN6219422) at dilution of 1:100 (40x lens).

IHC

Immunofluorescence analysis of C6 cells using p70 S6 Kinase 1 1 Rabbit pAb (ABIN3023168, ABIN3023169, ABIN3023170, ABIN1513490 and ABIN6219422) at dilution of 1:100 (40x lens).

Immunofluorescence analysis of U-2 OS cells using p70 S6 Kinase 1 1 Rabbit pAb (ABIN3023168, ABIN3023169, ABIN3023170, ABIN1513490 and ABIN6219422) at dilution of 1:100 (40x lens).

6 images

(2 references)

Catalog No. ABIN3023169

Datasheet as PDF

Target See all RPS6KB1 Antibodies

RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Binding Specificity
29

28

21

19

18

16

16

15

15

15

15

15

14

12

12

11

10

8

8

8

8

6

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 1-352
Reactivity
352

260

257

57

24

23

20

19

11

9

9

4

4

3

3

2

2

1
Human
Host
332

33

4

2
Rabbit
Compatible Secondaries
Clonality
335

36
Polyclonal
Conjugate
169

24

17

15

15

15

15

15

15

15

8

8

8

8

8

8

6

1

1

1
This RPS6KB1 antibody is un-conjugated
Application
292

147

104

92

91

75

66

32

24

24

20

8

7

4

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence

MRRRRRRDGF YPAPDFRDRE AEDMAGVFDI DLDQPEDAGS EDELEEGGQL NESMDHGGVG PYELGMEHCE KFEISETSVN RGPEKIRPEC FELLRVLGKG GYGKVFQVRK VTGANTGKIF AMKVLKKAMI VRNAKDTAHT KAERNILEEV KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL FMQLEREGIF MEDTACFYLA EISMALGHLH QKGIIYRDLK PENIMLNHQG HVKLTDFGLC KESIHDGTVT HTFCGTIEYM APEILMRSGH NRAVDWWSLG ALMYDMLTGA PPFTGENRKK TIDKILKCKL NLPPYLTQEA RDLLKKLLKR NAASRLGAGP GDAGEVQAHP FF

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human P70 S6K (NP_003152.1).

Isotype

IgG
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr229) antibody
RPS6KB1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) antibody
RPS6KB1 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 5G9 unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 416-525) antibody
RPS6KB1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2C2 unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 361-525) antibody
RPS6KB1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 91-352) antibody
RPS6KB1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr389), (pThr412) antibody
RPS6KB1 Reactivity: Human, Mouse, Rat, Pig WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pSer371) antibody
RPS6KB1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 416-525) antibody
RPS6KB1 Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 1E10 unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (AA 416-525) antibody
RPS6KB1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E12 unconjugated

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (C-Term) antibody
RPS6KB1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid freeze / thaw cycles

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

Guo, Hu, Chen, Li, Ye, Cheng, Zhang, He: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." in: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).
Target

RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Alternative Name

RPS6KB1 (RPS6KB1 Products)

Synonyms

PS6K antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, STK14A antibody, p70 S6KA antibody, p70(S6K)-alpha antibody, p70-S6K antibody, p70-alpha antibody, 10539 antibody, 7084 antibody, CG10539 antibody, DS6K antibody, Dmel\\CG10539 antibody, Dp70S6k antibody, Dp70[s6k] antibody, Dp70s6k antibody, S6k antibody, dS6K antibody, dS6k antibody, dp70[S6k] antibody, dp70s6k antibody, dps6k antibody, ds6k antibody, fs(3)07084 antibody, l(3)07084 antibody, p70 S6K antibody, p70/S6K antibody, p70S6K antibody, p70[S6 kinase] antibody, p70[S6K] antibody, p70[S6k] antibody, p70[S6kinase] antibody, p70s6K antibody, s6k antibody, s6k11 antibody, 2610318I15Rik antibody, 4732464A07Rik antibody, 70kDa antibody, AA959758 antibody, AI256796 antibody, AI314060 antibody, p70/85s6k antibody, p70s6k antibody, p70s6k-A antibody, p70-s6k antibody, ps6k antibody, rps6kb1 antibody, rps6kb1-A antibody, s6K1 antibody, stk14a antibody, fc51h01 antibody, wu:fc51h01 antibody, zgc:55713 antibody, ribosomal protein S6 kinase B1 antibody, Ribosomal protein S6 kinase antibody, ribosomal protein S6 kinase, polypeptide 1 antibody, ribosomal protein S6 kinase B1 L homeolog antibody, ribosomal protein S6 kinase B1 S homeolog antibody, ribosomal protein S6 kinase b, polypeptide 1b antibody, RPS6KB1 antibody, S6k antibody, Rps6kb1 antibody, rps6kb1.L antibody, rps6kb1.S antibody, rps6kb1b antibody

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.,PS6K,S6K,S6K-beta-1,S6K1,STK14A,p70 S6KA,p70(S6K)-alpha,p70-S6K,p70-alpha,P70 S6K,RPS6KB1,p70S6KA,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Protein Kinase C Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Cell cycle inhibitors,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Akt downstream targets,RPS6KB1

Molecular Weight

51 kDa/52 kDa/56 kDa/59 kDa

Gene ID

6198

UniProt

P23443

Pathways

PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect